References

  • [ 1 ]

    Johnson L, Luksch P, Ranfield J, Hardy C. The laboratory assessment of a new hemostat able to clot blood containing anticoagulants. Presented at the 21st Annual Symposium on Advanced Wound Care and the Wound Healing Society, San Diego, 2008

  • [ 2 ]

    Winstanley et al, 2018

  • [ 3 ]

    Johnson et al

  • [ 4 ]

    Millner, 2010

  • [ 5 ]

    Reference number 5

  • [ 6 ]

    Kozen BG, Kircher SJ, Henao J, Godinez FS, Johnson AS. An alternate hemostatic dressing: comparison of CELOX, HemCon, and QuikClot. Acad Emerg Med 2008; 15(1):74-81

  • Ageno W, Gallus AS, Wittkowsky A, Crowther M, Hylek EM, Palareti G. Oral anticoagulant therapy: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest 2012; 141(2 Suppl):e44S-e88S
  • Aiba S. Studies on chitosan: 4. Lysosymic hydrolysis of partially N-acetylated chitosans. Int J Biol Macromol 1992; 14(4):225-228 Alsarra IA. Chitosan topical gel formulation in the management of burn wounds. Int J Biol Macromol 2009; 45(1):16-21
  • Arnaud F, Parreño-Sadalan D, Tomori T, Delima MG, Teranishi K, Carr W, NcNamee G, McKeague A, Govindaraj K, Beadling C, Lutz C, Sharp T, Mog S, Burris D, MvCarron R. Comparison of 10 hemostatic dressings in a groin transection model in swine. J Trauma 2009a; 67(4):848-855
  • Arnaud F, Teranishi K, Tomori T, Carr W, McCarron R. Comparison of 10 hemostatic dressings in a groin puncture model in swine. J Vasc Surg 2009b; 50(3):632-639 Ashkani-Esfahani S, Emami Y, Esmaeilzadeh E, Bagheri F, Namazi MR. Glucosamine enhances tissue regeneration in the process of wound healing in rats as animal model: a stereological study. J Cytol Histol 2012; 3:1000150
  • Baldrick P. The safety of chitosan as a pharmaceutical excipient. Regul Toxicol Pharmacol 2010; 56(3):290-299
  • Bar J, David A, Khader T, Mulcare M, Tedeschi C. Assessing coagulation by rotational thromboelastometry (ROTEM) in rivaroxaban-anticoagulated blood using hemostatic agents. Prehosp Disaster Med 2017; 32(3):580-587
  • Barnard J, Millner R. A review of topical hemostatic agents for use in cardiac surgery. Ann Thorac Surg 2009; 88(4):1377-1383
  • Behrens AM, Sikorski MJ, Kofinas P. Hemostatic strategies for traumatic and surgical bleeding. J Biomed Mater Res A 2014; 102(11):4182-4194
  • Bennett BL, Littlejohn LF, Kheirabadi BS, Butler FK, Kotwal RS, Dubick MA, Bailey JA. Management of external hemorrhage in tactical combat casualty care: chitosan-based hemostatic gauze dressings – TCCC Guidelines – change 13-05. J Spec Oper Med 2014; 14(3):40-57
  • Bernkop-Schnurch A, Dunnhaupt S. Chitosan-based drug delivery systems. Eur J Pharm Biopharm 2012; 81(3):463-469
  • Bochicchio G, Kilbourne M, Kuehn R, Keledjian K, Hess J, Scalea T. Use of a modified chitosan dressing in a hypothermic coagulopathic grade V liver injury model. Am J Surg 2009; 198(5):617-622
  • Boucard N, Viton C, Agay D, Mari E, Roger T, Chancerelle Y, Domard A. The use of physical hydrogels of chitosan for skin regeneration following third-degree burns. Biomaterials 2007; 28(24):3478-3488
  • Boucher BA, Traub O. Achieving hemostasis in the surgical field. Pharmacotherapy 2009; 29(7 Pt 2):2S-7S
  • Brohi K, Singh J, Heron M, Coats T. Acute traumatic coagulopathy. J Trauma 2003; 54(6):1127-1130
  • Burgert JM, Gegel BT, Austin R 3rd, Davila A, Deeds J, Hodges L, Hover A, Lockhart C, Roy J, Simpson G, Weaver S, Wolfe W, Johnson D. Effects of arterial blood pressure on rebleeding using Celox and TraumaDEX in a porcine model of lethal femoral injury. AANA J 2010; 78(3):230-236
  • Burn J, Pirmohamed M. Direct oral anticoagulants versus warfarin: is new always better than the old? Open Heart 2018; 5(1):e000712
  • Camp MA. Hemostatic agents: a guide to safe practice for perioperative nurses. AORN J 2014; 100(2):131-147
  • Campbell HE, Stokes EA, Bargo DN, Curry N, Lecky FE, Edwards A, Woodford M, Seeney F, Eaglestone S, Brohi K, Gray AM, Stanworth SJ. Quantifying the healthcare costs of treating severely bleeding major trauma patients: a national study for England. Crit Care 2015; 19:276
  • Carrier M, Le Gal G, Wells PS, Rodger MA. Systematic review: case-fatality rates of recurrent venous thromboembolism and major bleeding events among patients treated for venous thromboembolism. Ann Intern Med 2010; 152(9):578-589
  • Chan LW, Kim CH, Wang X, Pun SH, White NJ, Kim TH. PolySTAT-modified chitosan gauzes for improved hemostasis in external hemorrhage. Acta Biomater 2016; 31:178-185
  • Charernsriwilaiwat N, Opanasopit P, Rojanarata T, Ngawhirunpat T. Lysozyme-loaded, electrospun chitosan-based nanofiber mats for wound healing. Int J Pharm 2012; 427(2):379-384
  • Cheung RCF, Ng, TB, Wong JH, Chan WY. Chitosan: an update on potential biomedical and pharmaceutical applications. Mar Drugs 2015; 13:5156-5186Chou TC, Fu E, Wu CJ, Yeh JH. Chitosan enhances platelet adhesion and aggregation. Biochem Biophys Res Commun 2003; 302(3):480-483
  • Chung YJ, An SY, Yeon JY, Shim WS, Mo JH. Effect of a chitosan gel on hemostasis and prevention of adhesion after endoscopic sinus surgery. Clin Exp Otorhinolaryngol 2016; 9(2):143-149
  • Conley SP, Littlejohn LF, Henao J, DeVito SS, Zarow GJ. Control of junctional hemorrhage in a consensus swine model with hemostatic gauze products following minimal training. Mil Med 2015; 180(11):1189-1195
  • Corral M, Ferko N, Hollmann S, Broder MS, Chang E. Health and economic outcomes associated with uncontrolled surgical bleeding: a retrospective analysis of the Premier Perspectives Database. ClinicoEcon Outcomes Res 2015; 7:409-421
  • Croisier F, Jérôme C. Chitosan-based biomaterials for tissue engineering. Eur Polym J 2013; 49:780-792
  • Crunkhorn R, Burnham R, Walton G. Successful use of a military-grade haemostatic agent for a major head and neck bleed. J Laryngol Otol 2013; 127(10):1031-1033
  • Dai TH, Tanaka M, Huang YY, Hamblin MR. Chitosan preparations for wounds and burns: antimicrobial and wound-healing effects. Expert Rev Anti-Infect Ther 2011; 9(7):857-879
  • Davie EW, Kulman JD. An overview of the structure and function of thrombin. Semin Thromb Hemost 2006; 32(Suppl 1):3-15
  • Douketis JD, Gu CS, Schulman S, Ghirarduzzi A, Pengo V, Prandoni P. The risk of fatal pulmonary embolism after discontinuing anticoagulant therapy for venous thromboembolism. Ann Intern Med 2007; 147(11):766-774
  • Douketis JD. Perioperative management of patients who are receiving warfarin therapy: an evidence based and practical approach. Blood 2011; 117(19):5044-5049
  • Dragostin OM, Samal SK, Dash M, Lupascu F, Panzariu A, Tuchilus C, Ghetu N, Danciu M, Dubruel P, Pieptu D, Vasile C, Tatia R, Profre L. New antimicrobial chitosan derivatives for wound dressing applications. Carbohydr Polym 2016; 141:28-40
  • Eason G., Hoggarth A., Alden M., Hardy C., & Ranfield J. (2010) The eect of Celox™ Vascular in a Vascular Access Model; The Symposium on Advanced Wound Care and The Wound Healing Society, Orlando, Florida, April 17-20, 2010, Gaylord Palms Hotel And Convention Center.
  • Evans JA, van Wessem KJ, McDougall D, Lee KA, Lyons T, Balogh ZJ. Epidemiology of traumatic deaths: comprehensive population-based assessment. World J Surg 2010; 34(1):158-163
  • Felt O, Carrel A, Baehni P, Buri P, Gurny R. Chitosan as tear substitute: a wetting agent endowed with antimicrobial efficacy. J Ocul Pharmacol 2000; 16(3):261-270
  • Fife CE, Carter MJ, Walker D, Thomson B. Wound care outcomes and associated cost among patients treated in US outpatient wound centers: data from the US Wound Registry. Wounds 2012; 24(1):10-17
  • Foda NH, El-Iaithy HM, Tadros MI. Implantable biodegradable sponges: effect of interpolymer complex formation of chitosan with gelatin on release behavior of tramadol hydrochloride. Drug Dev Ind Pharm 33(1):7-17
  • Frohm M, Gunne H, Bergman AC, Agerberth B, Bergman T, Boman A, Lidén S, Jörnvall H, Boman HG. Biochemical and antibacterial analysis of human wound and blister fluid. Eur J Biochem 1996; 237(1):86-92
  • Gegel BT, Burgert J, Cooley B, MacGregor J, Myers J, Calder S, Luellen R, Loughren M, Johnson D. The effects of BleedArrest, Celox, and TraumaDex on hemorrhage control in a porcine model. J Surg Res 2010; 164(1):e125-e129
  • Gerente C, Lee VKC, Le Cloirec P, McKay G. Application of chitosan for the removal of metals from wastewaters by adsorption – Mechanisms and models review. Crit Rev Environ Sci Technol 2007; 37:41-127
  • Ghadimi K, Levy JH, Welsby IJ. Perioperative management of the bleeding patient. Br J Anaesth 2016; 117(Suppl 3):iii18-iii30
  • Hatamabadi HR, Asayesh Zarchi F, Kariman H, Arhami Dolatabadi A, Tabatabaey A, Amini A. Celoxcoated gauze for the treatment of civilian penetrating trauma: a randomized clinical trial. Trauma Mon 2015; 20(1):e23862
  • Howling GI, Dettmar PW, Goddard PA, Hampson FC, Dornish M, Wood EJ. The effect of chitin and chitosan on the proliferation of human skin fibroblasts and keratinocytes in vitro. Biomaterials 2001; 22(22):2959-2966
  • Hu Z, Zhang DY, Lu ST, Li PW, Li SD. Chitosan-based composite materials for prospective hemostatic applications. Mar Drugs 2018; 16(8):273
  • Iyer P, Walker KJ, Madihally SV. Increased matrix synthesis by fibroblasts with decreased proliferation on synthetic chitosan-gelatin porous structures. Biotechnol Bioeng 2012; 109(5):1314-1325
  • Jayakumar R, Prabaharan M, Sudheesh Kumar PT, Nair SV, Tamura H. Biomaterials based on chitin and chitosan in wound dressing applications. Biotechnol Adv 29(3):322-337
  • Jin NZ, Gopinath SCB. Potential blood clotting factors and anticoagulants. Biomed Pharmacother 2016; 84:356-365
  • Johnson L, Luksch P, Ranfield J, Hardy C. The laboratory assessment of a new hemostat able to clot blood containing anticoagulants. Presented at the 21st Annual Symposium on Advanced Wound Care and the Wound Healing Society, San Diego, 2008
  • Joppa SA, Salciccioli J, Adamski J, Patel S, Wysokinski W, McBane R, Al-Saffar F, Esser H, Shamoun F. A practical review of the emerging direct anticoagulants, laboratory monitoring, and reversal agents. J Clin Med 2018; 7(2):pii:E29
  • Kheirabadi B. Evaluation of topical hemostatic agents for combat wound treatment. US Army Med Dep J 2011; Apr-Jun 25-37
  • Kheirabadi BS, Edens JW, Terrazas IB, Estep JS, Klemcke HG, Dubick MA, Holcomb JB. Comparison of new hemostatic granules/powders with currently deployed hemostatic products in a lethal model of extremity arterial hemorrhage in swine. J Trauma 2009; 66(2):316-326
  • Kheirabadi BS, Mace JE, Terrazas IB, Fedyk CG, Valdez KK, MacPhee MJ, Beall D, Estep JS, Dubick MA, Blackbourne LH. Clot-inducing minerals versus plasma protein dressing for topical treatment of external bleeding in the presence of coagulopathy. J Trauma 2010; 69(5):1062-1072
  • Khor E, Lim LY. Implantable applications of chitin and chitosan. Biomaterials 2003; 24(13):2339-2349
  • Klokkevold PR, Fukayama H, Sung EC, Bertolami CN. The effect of chitosan (poly-N-acetyl glucosamine) on lingual hemostasis in heparinized rabbits. J Oral Maxillofac Surg 1999; 57(1):49-52
  • Köksal Ö, Özdemir F, Çam Etöz B, İşbil Büyükcoşkun N, Siğirli D. Hemostatic effect of a chitosan linear polymer (Celox) in a severe femoral artery bleeding rat model under hypothermia or warfarin therapy. Turk J Trauma Emerg Surg 2011; 17(3):199-204
  • Kovich O, Otley CC. Thrombotic complications related to discontinuation of warfarin and aspirin therapy perioperatively for cutaneous operation. J Am Acad Dermatol 2003; 48(2):233-237
  • Kozen BG, Kircher SJ, Henao J, Godinez FS, Johnson AS. An alternate hemostatic dressing: comparison of CELOX, HemCon, and QuikClot. Acad Emerg Med 2008; 15(1):74-81
  • Kratz G, Arnander C, Swedenborg J, Back M, Falk C, Gouda I, Larm O. Heparin-chitosan complexes stimulate wound healing in human skin. Scand J Plast Reconstr Surg Hand Surg 1997; 31(2):119-123
  • Kuar RR, Glick JB, Siegel D. Achieving hemostasis in dermatology – Part 1: preoperative, intraoperative, and postoperative management. Indian Dermatol Online J 2013; 4(2):71-81
  • Lamb KM, Pitcher HT, Cavarocchi NC, Hirose H. Vascular site hemostasis in percutaneous extracorporeal membrane oxygenation therapy. Open Cardiovasc Thorac Surg J. 2012; 5:8-10
  • Lechner R, Helm M, Mueller M, Wille T, Friemert B. Efficacy of hemostatic agents in humans with rotational thromboelastometry: an in-vitro study. Mil Med 2016; 181(8):907-912
  • Lee DW, Lim H, Chong HN, Shim WS. Advances in chitosan material and its hybrid derivatives. Open Biomater 2009; 1(1):10-20
  • Lee G, Arepally GM. Anticoagulation techniques in apheresis: from heparin to citrate and beyond. J Clin Apher 2012; 27(3):117-125
  • Lee VF. Solution and shear properties of chitin and chitosan. Ph.D. Dissertation, University of Washington, University Microfilms, Ann Arbor, USA. 1974
  • Levin RM, Krieger NN, Winzler RJ. Glucosamine and acetylglucosamine tolerance in man. J Lab Clin Med 1961; 58:927-932
  • Li Q, Dunn ET, Grandmaison EW, Goosen MFA. Applications and properties of chitosan. J Bioact Compat Polym 1992; 7:370-397
  • Linkins LA, Choi PT, Douketis JD. Clinical impact of bleeding in patients taking oral anticoagulant therapy for venous thromboembolism: a meta-analysis. Ann Intern Med 2003; 139(11):893-900
  • Liu X, Guan Y, Yang D, Li Z, Yao K. Antibacterial action of chitosan and carboxymethylated chitosan. J Appl Polym Sci 2001; 79:1324-1335
  • Lootsik MD, Bilyy RO, Lutsyk MM, Stoika RS. Preparation of chitosan with high grade blood clotting activity and its hemostatic potential assessment. Biotechnol Acta 2015; 8(6):32-40
  • Lord MS, Cheng B, McCarthy SJ, Jung M, Whitelock JM. The modulation of platelet adhesion and activation by chitosan through plasma and extracellular matrix proteins. Biomaterials 2011; 32(28):6655-6662
  • MacIntyre AD, Quick JA, Barnes SL. Hemostatic dressings reduce tourniquet time while maintaining hemorrhage control. Am Surg 2011; 77(2):162-165
  • Madhok BM, Vowden K, Vowden P. New techniques for wound debridement. Int Wound J 2013; 10(3):247-251
  • Malette WG, Quigley HJ, Gaines RD, Johnson ND, Rainer WG. Chitosan: a new hemostatic. Ann Thorac Surg 1983; 36(1):55-58
  • Marietta M, Facchini L, Pedrazzi P, Busani S, Torelli G. Pathophysiology of bleeding in surgery. Transplant Proc 2006; 38(3):812-814
  • Martini WZ. Coagulation complications following trauma. Mil Med Res 2016; 3:35
  • Martyn D, Meckley LM, Miyasato G, Lim S, Riebman JB, Kocharian R, Scaife JG, Rao Y, Corral M. Variation in hospital resource use and cost among surgical procedures using topical absorbable hemostats. ClinicoEcon Outcomes Res 2015a; 7:567-574
  • Martyn D, Kocharian R, Lim S, Meckley LM, Miyasato G, Prifti K, Rao Y, Riebman JB, Scaife JG, Soneji Y, Corral M. Reduction in hospital costs and resource consumption associated with the use of advanced topical hemostats during inpatient procedures. J Med Econ 2015b; 18(6):474-481
  • McCarty MF. Glucosamine for wound healing. Med Hypotheses 1996; 47(4):273-275
  • Mercy HP, Halim AS, Hussein AR. Chitosan-derivatives as hemostatic agents: their role in tissue regeneration. Regen Res 1(1):38-46
  • Millner R, Lockhart AS, Marr R. Chitosan arrests bleeding in major hepatic injuries with clotting dysfunction: an in vivo experimental study in a model of hepatic injury in the presence of moderate systemic heparinisation. Ann R Coll Surg Engl 2010; 92(7):559-561
  • Millner RW, Lockhart AS, Bird H, Alexiou C. A new hemostatic agent: initial life-saving experience with Celox (chitosan) in cardiothoracic surgery. Ann Thorac Surg 2009; 87(2):e13-e14
  • Millner RWJ, Lockhart AS, Marr R, Jones K. Omni-Stat (chitosan) arrests bleeding in heparinised subjects in vivo: an experimental study in a model of major peripheral vascular injury. Eur J Cardiothorac Surg 2011; 39(6):952-954
  • Mirzadehl H, Yaghobi N, Amanpour S, Ahmadi H, Ali Mohagheghi M, Hormozi F. Preparation of chitosan derived from shrimp’s shell of Persian Gulf as a blood hemostasis agent. Iranian Polym J 2002; 11(1):63-68
  • Misgav M, Lubetszki A, Brutman-Barazani T, Martinowitz U, Kenet G. The hemostatic efficacy of chitosanpads in hemodialysis patients with significant bleeding. J Vasc Access 2017; 18(3):220-224
  • Mitra B, Tullio F, Cameron PA, Fitzgerald M. Trauma patients with the ‘triad of death’. Emerg Med J 2012; 29(8):622-625
  • Mohandas A, Deepthi S, Biswas R, Jayakumar R. Chitosan based metallic nanocomposite scaffolds as antimicrobial wound dressings. Bioact Mater 2018; 3(3):267-277
  • Monaco L, Biagi C, Conti V, Melis M, Donati M, Venegoni M, Vaccheri A, Motola D. Safety profile of the direct oral anticoagulants: an analysis of the WHO database of adverse drug reactions. Br J Clin Pharmacol 2017; 83(7):1532-1543
  • Mulloy B, Hogwood J, Gray E, Lever R, Page CP. Pharmacology of heparin and related drugs. Pharmacol Rev 2016; 68(1):76-141
  • Niekraszewicz A. Chitosan medical dressings. Fibres and Textiles in Eastern Europe vol. 13 2005; 6(54):16-18
  • Niles SE, McLaughlin DF, Perkins JG, Wade CE, Li Y, Spinella PC, Holcomb JB. Increased mortality associated with the early coagulopathy of trauma in combat casualties. J Trauma 2008; 64(6):1459-1463
  • Ong SY, Wu J, Moochhala SM, Tan MH, Lu J. Development of a chitosan-based wound dressing with improved hemostatic and antimicrobial properties. Biomaterials 2008; 29(32):4323-4332
  • Peng T. Biomaterials for haemorrhage control. Trends Biomater Artif Organs 2010; 24(1):27-68
  • Pogorielov M, Kalinkevich O, Deineka V, Garbuzova V, Solodovnik A, Kalinkevich A, Kalinichenko T, Gapchenko A, Sklyar A, Danilchenko S. Haemostatic chitosan coated gauze: in vitro interaction with human blood and in-vivo effectiveness. Biomater Res 2015; 19:22
  • Pogorielov MV, Siroka VZ. Chitosan as a hemostatic agent: current state. Eur J Med B 2015; 2(1):24-33
  • Pozza M, Millner RWJ. Celox (chitosan) for haemostasis in massive traumatic bleeding: experience in Afghanistan. Eur J Emerg Med 2011; 18(1):31-33
  • Rall JM, Cox JM, Songer A, Comeaux JA, Estep JS, Cestero RF, Ross JD. Comparison of novel hemostatic dressings with QuikClot combat gauze in a standardized swine model of uncontrolled haemorrhage. J Trauma Acute Care Surg 2013; 75(2 Suppl 2):S150-S156
  • Rao SB, Sharma CP. Use of chitosan as a biomaterial: studies on its safety and hemostatic potential. J Biomed Mater Res 1997; 34(1):21-28
  • Recinos G, Inaba K, Dubose J, Demetriades D, Rhee P. Local and systemic hemostatics in trauma: a review. Turk J Trauma Emerg Surg 2008; 14(3):175-181
  • Saap LJ, Falanga V. Debridement performance index and its correlation with complete closure of diabetic foot ulcers. Wound Repair Regen 2002; 10(6):354-359
  • Schierle C, Krol J. Can new hemostatic dressings facilitate sharp debridement in high-risk patients? Podiatry Today 2009; 22(7):20-22
  • Schreiber MA, Neveleff DJ. Achieving hemostasis with topical hemostats: making clinically and economically appropriate decisions in the surgical and trauma settings. AORN J 2011; 94(5):S1-S20
  • Seyednejad H, Imani M, Jamieson T, Seifalian AM. Topical haemostatic agents. Br J Surg 2008; 95(10):1197-1225
  • Seyfarth F, Schliemann S, Elsner P, Hipler UC. Antifungal effect of high- and low-molecular-weight chitosan hydrochloride, carboxymethyl chitosan, chitosan oligosaccharide and N-acetyl-D-glucosamine against Candida albicans, Candida krusei and Candida glabrata. Int J Pharm 2008; 353(1-2):139-148
  • Shander A. Financial and clinical outcomes associated with surgical bleeding complications. Surgery 2007; 142(4 Suppl):S20-S25
  • Singla AK, Chawla M. Chitosan: some pharmaceutical and biological aspects – an update. J Pharm Pharmacol 2001; 53(8):1047-1067
  • Snyder RJ, Sigal BD. Evaluation of hemostatic gauze versus standard of care for the treatment of chronic wounds in the presence of anticoagulants. Presented as a poster at SAWC 2013
  • Snyder RJ, Sigal BD. The importance of hemostasis in chronic wound care: an open-label controlled clinical study of OMNI-STAT (chitosan) versus standard of care in post-debridement treatment of patients with chronic wounds with or without concomitant use of anticoagulants. Wound Care Hyperb Oxygen 2013; 4(2):9-16
  • Spotnitz WD, Burks S. Hemostats, sealants, and adhesives: components of the surgical toolbox. Transfusion 2008; 48(7):1502-1516
  • Spotnitz WD, Burks S. State-of-the-art review: hemostats, sealants, and adhesives II: update as well as how and when to use the components of the surgical toolbox. Clin Appl Thromb Hemost 2010; 16(5):497-514
  • Spyropoulos AC, Douketis JD. How I treat anticoagulated patients undergoing an elective procedure or surgery. Blood 2012; 120(15):2954-2962
  • Stacy Z, Richter S. Practical considerations for the use of direct oral anticoagulants in patients with atrial fibrillation. Clin Appl Thromb Hemost 2017; 23(1):5-19
  • Stephen-Haynes J, Gibson E, Greenwood M. Chitosan: a natural solution for wound healing. J Community Nurs 2014; 28(1):48-53
  • Stępniewski M, Martynkiewicz J, Gosk J. Chitosan and its composites: properties for use in bone substitution. Polim Med 2017; 47(1):49-53
  • Stokes ME, Ye X, Shah M, Mercaldi K, Reynolds MW, Rupnow MF, Hammond J. Impact of bleeding-related complications and/or blood product transfusions on hospital costs in inpatient surgical patients. BMC Health Serv Res 2011; 11:135
  • Stricker-Krongrad, AH, Alikhassy Z, Matsangos N, Sebastian R, Marti G, Lay F, Harmon JW. Efficacy of chitosan-based dressing for control of bleeding in excisional wounds. Eplasty 2018; 18:122-130
  • Suzuki K, Cowan L. Current concepts in wound debridement. Podiatry Today 2009; 22(7):40-48
  • Suzuki Y, Okamoto Y, Morimoto M, Sashiwa H, Saimoto H, Tanioka SI, Shigemasa Y, Minami S. Influence of physico-chemical properties of chitin and chitosan on complement activation. Carbohydr Polym 2000; 42(3):307-310
  • Tan ECTH, Bleeker CP. Field experience with a chitosan-based haemostatic dressing. MCI Forum 2011; 3(4):11-15
  • Tashiro T. Antibacterial and bacterium absorbing macromolecules. Macromol Mater Eng 2001; 286:63-87
  • Thibodeaux, KT, Speyrer, MS, Thibodeaux, RP, Rogers, AA, Rippon, MG. Management of postoperative bleeding in surgically debrided wounds: topical haemostat versus electrocautery. Journal of Wound Care 2020; 29(8): 444-451
  • Trabattoni D, Montorsi P, Fabbiocchi F, Lualdi A, Gatto P, Bartorelli A. A new kaolin-based haemostatic bandage compared with manual compression for bleeding control after percutaneous coronary procedures. Eur Radiol 2011; 21(8):1687-1691
  • Ueno H, Yamada H, Tanaka I, Kaba N, Matsuura M, Okumura M, Kadosawa T, Fujinaga T. Accelerating effects of chitosan for healing at early phase of experimental open wounds in dogs. Biomaterials 1999; 20(15):1407-1414
  • Waibel KH, Haney B, Moore M, Whisman B, Gomez R. Safety of chitosan bandages in shellfish allergic patients. Mil Med 2011; 176(10):1153-1156
  • Wang T, Zhu XK, Xue XT, Wu DY. Hydrogel sheets of chitosan, honey and gelatin as burn wound dressings. Carbohydr Polym 2012; 88(1):75-83
  • Watters JM, Van PY, Hamilton GJ, Sambasivan C, Differding JA, Schreiber MA. Advanced hemostatic dressings are not superior to gauze for care under fire scenarios. J Trauma 2011; 70(6):1413-1419
  • Winstanley M, Smith JE, Wright C. Catastrophic haemorrhage in military major trauma patients: a retrospective database analysis of haemostatic agents used on the battlefield. J R Army Med Corps 2018;0:1-5.
  • Whang HS, Kirsch W, Zhu YH, Yang CZ, Hudson SM. Hemostatic agents derived from chitin and chitosan. J Macromolec Sci, Part C 2005; 45(4):309-323
  • Won KB, Lee SH, Chang HJ, Shim CY, Hong GR, Ha JW, Chung N. Safety and cost-effectiveness of bridge therapies for invasive dental procedures in patients with mechanical heart valves. Yonsei Med J 2014; 55(4):937-943
  • Xia WS. Physiological activities of chitosan and its application in functional foods. J Chinese Inst Food Sci Tech 2003; 3:77-81
  • Yang J, Tian F, Wang Z, Wang Q, Zeng YJ, Chen SQ. Effect of chitosan molecular weight and deacetylation degree on hemostasis. J Biomed Mater Res B Appl Biomater 2008; 84(1):131-137
  • Yang TL. Chitin-based materials in tissue engineering: applications in soft tissue and epithelial organ. Int J Mol Sci 2011; 12(3):1936-1963
  • Zhang YL, Gao B, Liu XW. Topical and effective hemostatic medicines in the battlefield. Int J Clin Exp Med 2015; 8(1):10-19
  • Zimmerman LH. Causes and consequences of critical bleeding and mechanisms of blood coagulation. Pharmacotherapy 2007; 27(9 Pt 2):45S-56S

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